Endocrine Abstracts

BACKGROUND Recent evidence has suggested that minor degrees of thyroid dysfunction are associated with adverse outcomes and this argues for tight control of thyroid hormone replacement. Thyroxine (T4) tablets are available in 25, 50 and 100 microgram strengths in the UK but some patients require doses which cannot be obtained with these strengths. We have examined data from a thyroid register to determine the proportion of patients whose mean daily T4 dose cannot be achieved w...